Associated issues in MBL deficiency

At present there is no conclusive evidence to support the association of MBL deficiency with the development of particular medical conditions.

Doctors will monitor patients’ health by clinical review (check-up) and infrequent blood tests. Most patients will be looked after by their GP in the long term unless a clinical immunologist has identified any complications or additional immune problems.


Good protection against common bacteria and viruses, in keeping with the recommended vaccine schedule, will help reduce infections in patients with MBL
deficiency. Most vaccines are safe to be given to patients with MBL deficiency.
The annual flu vaccine is usually advised.

Immunologists may test vaccine responses to make sure that no other subtle immune defects, such as specific antibody deficiency, are contributing to MBL
deficiency to cause frequent infection.