Future prospects for HLH

The outlook for children with HLH has improved, owing to better recognition of the condition and better diagnostic tests so that treatment can start as quickly as possible. New types of medicine are also being developed to treat HLH. Treatment is intensive and has side effects but many of these can be managed. HSCT remains the only cure for primary HLH but in many cases means that
children can lead a normal life afterwards.

In the inherited forms of HLH, genetic counselling for the family is important. Prenatal diagnosis is available for future pregnancies, provided that the faulty gene can be identified.